Myeloid Tests

CBS Labs offers Next Generation Sequencing to identify somatic mutations in myeloid malignancies. Our Panel covers 15 full genes (exomes only) and 39 additional genes where oncogenic hotspots are covered, providing a comprehensive assessment of the key genes involved in myeloid malignancies; all with a single test.

The panel consists of target genes frequently mutated in:

Acute myeloid leukemia (AML)
Myelodysplastic syndrome (MDS)
Myeloproliferative neoplasms (MPN)
Chronic myelogenous leukemia (CML)
Chronic myelomonocytic leukemia (CMML)
Juvenile myelomonocytic leukemia (JMML)

Gene List:

 

ABL1 CEBPA HRAS MYD88 SF3B1
ASXL1 CSF3R IDH1 NOTCH1 SMC1A
ATRX CUX1 IDH2 NPM1 SMC3
BCOR DNMT3A IKZF1 NRAS SRSF2
BCOR L1ETV6/TEL JAK2 PDGFRA STAG2
BRAF EZH2 JAK3 PHF6 TET2
CALR FBXW7 KDM6A PTEN TP53
CBL FLT3 KIT PTPN11 U2AF1
CBLB GATA1 KRAS RAD21 WT1
CBLC GATA2 MLL RUNX1 ZRSR2
CDKN2A GNAS MPL SETBP1